Author: Steinrucken, H. C.; Amrhein, N.
Description: The broadspectrum herbicide glyphosate (N-[phosphonomethyl]-glycine), which causes the accumulation of shikimic acid in plant tissues, inhibits the enzymatic conversion of shikimic acid to anthranilic acid in a cell-free extract of Aerobacter, aerogenes 50% at 5 to 7 uM concentrations. Of the four enzymes involved in the transformation, only 5-enolpyruvylshikimic acid-3-phosphate synthase is inhibited by the herbicide.
Subject headings: Enzymes; Glyphosate; Metabolism; Physiology; Weeds; Plants; Eukaryotes
Publication year: 1980
Journal or book title: Biochemical and Biophysical Research Communications
Volume: 94
Issue: 4
Pages: 1207-1212
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Serial number: 4103