Author: Raymond, G.V.; Bauman, M.L.; Kemper, T.L.
Description: Autism is a behaviorally defined syndrome in which neuropathological abnormalities have been identified in the limbic system and cerebellum. The morphology of hippocampal neurons in two cases of infantile autism was studied and compared to age-matched controls. CA4 neurons in autistic children were smaller in perikaryon area and dendritic branching of both CA4 and CA1 neurons was less than in controls. These findings are consistent with previous studies and suggest a curtailment in maturation in the pathogenesis of autism.
Subject headings: Adolescent; Autistic Disorder/pathology; Child; Child, Preschool; Dendrites/pathology; Fatal Outcome; Female; Golgi Apparatus/chemistry/pathology; Hippocampus/pathology; Humans; Male; Staining and Labeling; Autism
Publication year: 1996
Journal or book title: Acta Neuropathologica
Volume: 91
Issue: 1
Pages: 117-119
Find the full text : https://experts.umn.edu/en/publications/hippocampus-in-autism-a-golgi-analysis
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Type: Journal Article
Serial number: 79