Author: Cao, Q.; Li, J. & Wang, E.
Description: Fluorescent copper nanomaterials (CuNMs), including copper nanoparticles (CuNPs) and copper nanoclusters (CuNCs), become more and more popular with the abundant raw materials and low cost. A wide range of applications has been explored due to their fascinating properties such as low toxicity, remarkable water solubility, facile synthesis, large Stokes shifts, and good biocompatibility. As a kind of genetic material, DNA exhibits its molecular recognition function and diversity. The marriage between CuNMs and DNA endows DNA-templated CuNMs (DNA-CuNMs) with unique properties such as fluorescence, electrochemiluminescence and catalytic features. In this review, we summarize the synthesis and recent applications of DNA-CuNMs. Fluorescent CuNMs can be grown on various DNA scaffolds with special sequence design. T base plays an important role in the formation of CuNMs on DNA templates. These fluorescent DNA-CuNMs hold great prospect in logic gate construction, staining and biosensing of DNAs and RNAs, ions, proteins and enzymes, small molecules and so on.
Subject headings: Animals; Biosensing Techniques, methods; Copper, chemistry; DNA, chemistry; Fluorescence; Fluorescent Dyes, chemistry; Humans; Nanostructures, chemistry; Nanotechnology, methods; Nucleic Acids, analysis; Proteins, analysis; Biosensing; Copper nanomaterials; DNA; Fluorescence; Logical operation; Nanoclusters
Publication year: 2019
Journal or book title: Biosensors & bioelectronics
Volume: 132
Pages: 333-342
Find the full text: https://www.sciencedirect.com/science/article/abs/pii/S0956566319300752
Find more like this one (cited by): https://scholar.google.com/scholar?cites=17615494959710929553&as_sdt=5,26&sciodt=0,26&hl=en
Type: Journal article
Serial number: 3080