Preparation of opium alkaloids by palladium catalyzed bis-cyclizations. Formal total synthesis of morphine

Hong, C.Y., Overman, L.E. (1994)

Tetrahedron Letters, 35(21), 3453-3456

Palladium catalyzed cyclization of hydroisoquinoline diene to afford the pentacyclic opiate is the central step in a new synthesis of opium alkaloids.

Subject headings: Opium alkaloids; Palladium; Morphine; Synthesis

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Type: Journal Article

Serial number: 1790