Proteomic pattern-based analyses of light responses in Arabidopsis thaliana wild-type and photoreceptor mutants

Author: Kim, D.S.; Cho, D.S.; Park, W.-M.; Na, H.J.; Nam, H.G.

Description: Light critically affects the physiology of plants. Using two-dimensional gel electrophoresis, we used a proteomics approach to analyze the responses of Arabidopsis thaliana to red (660 nm), far-red (730 nm) and blue (450 nm) light, which are utilized by type II and type I phytochromes, and blue light receptors, respectively. Under specific light treatments, the proteomic profiles of 49 protein spots exhibited over 1.8-fold difference in protein abundance, significant at p <0.05. Most of these proteins were metabolic enzymes, indicating metabolic changes induced by light of specific wavelengths. The differentially-expressed proteins formed seven clusters, reflecting co-regulation. We used the 49 differentially-regulated proteins as molecular markers for plant responses to light, and by developing a procedure that calculates the Pearson correlation distance of cluster-to-cluster similarity in expression changes, we assessed the proteome-based relatedness of light responses for wild-type and phytochrome mutant plants. Overall, this assessment was consistent with the known physiological responses of plants to light. However, we also observed a number of novel responses at the proteomic level, which were not predicted from known physiological changes.

Subject headings: Arabidopsis/metabolism/radiation effects; Arabidopsis Proteins/biosynthesis; Cluster Analysis; Electrophoresis, Gel, Two-Dimensional; Light; Photosynthetic Reaction Center Complex Proteins/genetics/physiology; Phytochrome/genetics/physiology; Proteome/biosynthesis; Signal Transduction

Publication year: 2006

Journal or book title: Proteomics

Volume: 6

Issue: 10

Pages: 3040-3049

Find the full text : http://onlinelibrary.wiley.com/doi/10.1002/pmic.200500670/abstract

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Type: Journal Article

Serial number: 275