Author: Pratt, L.A.; Hsing, W.; Gibson, K.E.; Silhavy, T.J.
Description: In Escherichia coli, levels of the two major outer membrane porin proteins, OmpF and OmpC, are regulated in response to a variety of environmental parameters, and numerous factors have been shown to influence porin synthesis. EnvZ and OmpR control porin-gene transcription in response to osmolarity, and the antisense RNA, MicF, influences ompF translation. In contrast to these characterized factors, some of the components reported to influence porin expression have only modest effects and/or act indirectly. For others, potential regulatory roles, although intriguing, remain elusive. Here we review many of the components that have been reported to influence porin expression, address the potential regulatory nature of these components, and discuss how they may contribute to a regulatory network controlling porin synthesis.
Subject headings: Acids; Bacterial Outer Membrane Proteins/biosynthesis/metabolism; Bacterial Proteins; DNA, Bacterial; DNA-Binding Proteins/metabolism; Escherichia coli/growth & development/metabolism; Temperature; Toxins, Biological/toxicity; Water-Electrolyte Balance
Publication year: 1996
Journal or book title: Molecular Microbiology
Volume: 20
Issue: 5
Pages: 911-917
Find the full text : https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2958.1996.tb02532.x
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Type: Journal Article
Serial number: 1364