Tetrahydrofuran-containing macrolides: a fascinating gift from the deep sea

Author: Lorente, A.; Lamariano-Merketegi, J.; Albericio, F.; Alvarez, M.

Description: Marine organisms have produced a big number of structurally diverse secondary metabolites with important biological activities as a defense mechanism to the persistent aggression of their environment. (1) This structural diversity makes marine natural products excellent candidates for the investigation of new bioactive molecules with high pharmacological potential.

Subject headings: Aquatic Organisms/metabolism; Furans/chemistry; Macrolides/chemistry/metabolism; Oceans and Seas; Polyketides/chemistry/metabolism

Publication year: 2013

Journal or book title: Chemical Reviews

Volume: 113

Issue: 7

Pages: 4567-4610

Find the full text : https://pubs.acs.org/doi/full/10.1021/cr3004778?casa_token=nCp_h4yL5HkAAAAA:Xid6meJlsZyWPuPPianWEJrpAsDhpTiVEVVGJYWMmWJSKIQx6Unhc64SbsuFpIAH036_HOzkzkLCr59A

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Type: Journal Article

Serial number: 1450