Long-term survival during stationary phase: evolution and the GASP phenotype

Author: Finkel, S.E.

Description: The traditional view of the stationary phase of the bacterial life cycle, obtained using standard laboratory culture practices, although useful, might not always provide us with the complete picture. Here, the traditional three phases of the bacterial life cycle are expanded to include two additional phases: death phase and long-term stationary phase. In many natural environments, bacteria probably exist in conditions more akin to those of long-term stationary-phase cultures, in which the expression of a wide variety of stress-response genes and alternative metabolic pathways is essential for survival. Furthermore, stressful environments can result in selection for mutants that express the growth advantage in stationary phase (GASP) phenotype.

Subject headings: Bacteria/genetics/growth & development; Evolution, Molecular; Genetic Variation; Mutation; Phenotype; SOS Response (Genetics); Selection, Genetic

Publication year: 2006

Journal or book title: Nature Reviews. Microbiology

Volume: 4

Issue: 2

Pages: 113-120

Find the full text : https://www.nature.com/articles/nrmicro1340

Find more like this one (cited by): https://scholar.google.com/scholar?cites=3757938361278829037&as_sdt=1000005&sciodt=0,16&hl=en

Type: Journal Article

Serial number: 1581