Author: Shanthan Rao, P.; Venkataratnam, R.V.
Description: The Knoevenagel condensation of carbonyl substrates with acidic methylene reagents proceeds smoothly in presence of zinc chloride, without the need for solvent, to produce products of good purity in high yield. Carbonyl-methylene condensation products were prepared from aromatic aldehydes and substituted acetonitriles using zinc chloride as catalyst.
Subject headings: Knoevenagel condensation; Zinc chloride; Catalyst
Publication year: 1991
Journal or book title: Tetrahedron Letters
Volume: 32
Issue: 41
Pages: 5821-5822
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Type: Journal Article
Serial number: 1660