Author: Sreedhar, B.; Reddy, P.S.; Kumar, N.S.
Description: An efficient method is described for the regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles in high yields from a variety of Baylis–Hillman acetates and terminal alkynes with sodium azide using CuI as a catalyst, in either water or polyethylene glycol (PEG). This procedure is operationally simple and environmentally benign. Polyethylene glycol (PEG) serves as an efficient reusable solvent with higher efficiency.
Subject Headings: 1,4-Disubstituted 1,2,3-triazoles; 1,3-Dipolar cycloaddition; PEG; Water; CuI
Publication year: 2006
Journal or book title: Tetrahedron Letters
Volume: 47
Issue: 18
Pages: 3055-3058
Find the full text : https://www.sciencedirect.com/science/article/pii/S0040403906004552
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Type: Journal Article
Serial number: 2847