Indium-mediated reduction of hydroxylamines to amines

Author: Cicchi, S.; Bonanni, M.; Cardona, F.; Revuelta, J.; Goti, A.

Description: A novel and simple procedure for reduction of hydroxylamines to the corresponding amines by means of indium powder in aqueous media is reported. Applicability to one-pot reactions and isoxazolidine N-O bond reduction is also demonstrated. A catalytic version of the process using 2-5% In in the presence of other metals (Zn, Al) has been successfully developed.

Subject headings: Hydroxylamines; Reduction; Amines; Indium

Publication year: 2003

Journal or book title: Organic Letters

Volume: 5

Issue: 10

Pages: 1773-1776

Find the full text : https://pubs.acs.org/doi/abs/10.1021/ol034434l

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Type: Journal Article

Serial number: 1757