Author: Dondorp, A.M.; Kager, P.A.; Vreeken, J.; White, N.J.
Description: Obstruction of the microcirculation plays a central role in the pathophysiology of severe malaria. Here, Arjen Dondorp and colleagues describe the various contributors to impaired microcirculatory flow in falciparum malaria: sequestration, rosetting and recent findings regarding impaired red blood cell deformability. The correlation with clinical findings and possible therapeutic consequences are discussed.
Subject headings: Severe malaria; Microcirculatory flow; Red blood cell deformability; Exchange transfusion; Sequestration; Rosetting
Publication year: 2000
Journal or book title: Parasitology Today
Volume: 16
Issue: 6
Pages: 228-232
Find the full text:Â https://www.sciencedirect.com/science/article/pii/S0169475800016665
Find more like this one (cited by): https://scholar.google.com/scholar?cites=17046796368916281780&as_sdt=1000005&sciodt=0,16&hl=en
Type: Journal Article
Serial number: 1796