Author: Heuer, H.; Schmitt, H.; Smalla, K.
Description: The usage of antibiotics in animal husbandry has promoted the development and abundance of antibiotic resistance in farm environments. Manure has become a reservoir of resistant bacteria and antibiotic compounds, and its application to agricultural soils is assumed to significantly increase antibiotic resistance genes and selection of resistant bacterial populations in soil. The genome location of resistance genes is likely to shift towards mobile genetic elements such as broad-host-range plasmids, integrons, and transposable elements. Horizontal transfer of these elements to bacteria adapted to soil or other habitats supports their environmental transmission independent of the original host. The human exposure to soil-borne resistance has yet to be determined, but is likely to be severely underestimated.
Subject headings: Agriculture/methods; Animals; Anti-Bacterial Agents/pharmacology; Bacteria/drug effects/genetics; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Humans; Interspersed Repetitive Sequences; Manure/microbiology; Selection, Genetic
Publication year: 2011
Journal or book title: Current Opinion in Microbiology
Volume: 14
Issue: 3
Pages: 236-243
Find the full text :Â https://www.sciencedirect.com/science/article/pii/S1369527411000579
Find more like this one (cited by): https://scholar.google.com/scholar?cites=6447093736365715317&as_sdt=1000005&sciodt=0,16&hl=en
Type: Journal Article
Serial number: 1955