Author: Singh, S.K.; Koshkin, A.A.; Wengel, J.; Nielsen, P.
Description: A novel class of nucleic acid analogues, termed LNA (locked nucleic acids), is introduced. Following the Watson-Crick base pairing rules, LNA forms duplexes with complementary DNA and RNA with remarkably increased thermal stabilities and generally improved selectivities.
Subject Headings: Locked nucleic acids; Synthesis; Acid recognition
Publication year: 1998
Journal or book title: Chemical Communications
Issue: 4
Pages: 455-456
Find the full text : https://pubs.rsc.org/en/content/articlehtml/1998/cc/a708608c
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Type: Journal Article
Serial number: 2233