Author: Chen, I.; Dubnau, D.
Description: Naturally competent bacteria are able to take up exogenous DNA and undergo genetic transformation. The transport of DNA from the extracellular milieu into the cytoplasm is a complex process, and requires proteins that are related to those involved in the assembly of type IV pili and type II secretion systems, as well as a DNA translocase complex at the cytoplasmic membrane. Here, we will review the current knowledge of DNA transport during transformation.
Subject Headings: Bacteria/genetics/metabolism; Bacterial Proteins/metabolism; Biological Transport, Active; Cytoplasm/metabolism; DNA, Recombinant/genetics/metabolism; Fimbriae, Bacterial/metabolism; Gram-Negative Bacteria/genetics/metabolism; Gram-Positive Bacteria/genetics/metabolism; Models, Biological; Transformation, Genetic
Publication year: 2004
Journal or book title: Nature Reviews. Microbiology
Volume: 2
Issue: 3
Pages: 241-249
Find the full text : http://web.biosci.utexas.edu/psaxena/BIO366/articles/050801DNA%20transformation.pdf
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Type: Journal Article
Serial number: 2710