The origin of muscle fasciculations and cramps

Author: Layzer, R.B.

Description: The anatomic site of origin of muscle fasciculations and cramps has been debated for many years. Many authors have argued for a central origin of the abnormal discharges in the anterior horn cells. However, most of the evidence favors a very distal origin in the intramuscular motor nerve terminals. The factors giving rise to these discharges are not well understood. Fasciculations may be related to chemical excitation of motor nerve terminals, whereas cramps may result from mechanical excitation of motor nerve terminals during muscle shortening.

Subject Headings: Fasciculation/physiopathology; Humans; Muscle Cramp/*physiopathology; Muscles/innervation; Nerve Block

Keywords: The origin of muscle fasciculations and cramps

Publication year: 1994

Journal or book title: Muscle & Nerve

Volume: 17

Issue: 11

Pages: 1243-1249

Find the full text : https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.880171102

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Type: Journal Article

Serial number: 2552