Author: Yang, B.; Lian, Y.; Liu, Y.; Wu, B.-Y.; Duan, R.-S.
Description: Antecedent infections have been found to be the most common trigger for Guillain-Barre syndrome (GBS). In the present study, we retrospectively analyzed 36 adult patients with GBS and found that surgery, trauma and treatment with ganglioside were also common before the onset of GBS. The proportion of the axonal subtype of GBS in post-surgical/traumatic patients was higher than that in non-surgical/traumatic patients (P=0.013) in the present study. In conclusion, this study has shown that prior infection, surgery, trauma and ganglioside may be clinical contributors to the onset of GBS and raised the possibility that they may act synergistically as triggers for the development of GBS.
Subject Headings: Adult; Brain Injuries/complications; Chi-Square Distribution; Electromyography; Female; Gangliosides/adverse effects/immunology; Guillain-Barre Syndrome/diagnosis/etiology; Humans; International Classification of Diseases; Male; Middle Aged; Neural Conduction/physiology; Postoperative Complications/physiopathology; Retrospective Studies; Risk Factors; Ganglioside; Guillain-Barre syndrome; Infection; Surgery; Trauma
Keywords: A retrospective analysis of possible triggers of Guillain-Barre syndrome
Publication year: 2016
Journal or book title: Journal of Neuroimmunology
Volume: 293
Issue:
Pages: 17-21
Find the full text :Â https://www.sciencedirect.com/science/article/pii/S016557281630025X
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Type: Journal Article
Serial number: 2586