Author: Priess, J. R.; Schnabel, H.; Schnabel, R.
Description: Interactions between the early blastomeres in a C. elegans embryo are required for the specification of certain cell fates. Blastomeres that produce neurons and skin cells when cultured in isolation are induced to also produce pharyngeal cells in intact embryos. We have identified maternal effect lethal mutations that, on the basis of phenotype and temperature-sensitive period, appear to disrupt this inductive interaction. These mutations are all alleles of glp-1, a gene also involved in the control of germ cell proliferation during postembryonic development of C. elegans.
Subject headings: Alleles; Animals; Caenorhabditis elegans, embryology, genetics, physiology; Cell Communication; Embryo; Nonmammalian, ultrastructure; Embryonic and Fetal Development; Genes; Genes, Lethal; Infertility, genetics; Mutation; C elegans
Publication year: 1987
Journal or book title: Cell
Volume: 51
Issue: 4
Pages: 601-611
Find the full text: https://www.sciencedirect.com/science/article/abs/pii/0092867487901292
Find more like this one (cited by): https://scholar.google.com/scholar?cites=340896594345968623&as_sdt=1000005&sciodt=0,16&hl=en
Serial number: 3662
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