The red pigment prodigiosin is not an essential virulence factor in entomopathogenic Serratia marcescens

Author: Zhou, Wei; Li, JingHua; Chen, Jie; Liu, XiaoYuan; Xiang, TingTing; Zhang, Lin; Wan, YongJi

Description: Although pigments produced by pathogenic microbes are generally hypothesized as essential virulence factors, the role of red pigment prodigiosin in the pathogenesis of entomopathogenic Serratia marcescens is not clear. In this study, we analyzed the pathogenicity of different pigmented S. marcescens strains and their non-pigmented mutants in silkworms. Each pigmented strain and the corresponding non-pigmented mutants showed very similar LD50 value (statistically no difference), but caused very different symptom (color of the dead larva). Our results clearly indicated that the red pigment prodigiosin is not an essential virulence factor in entomopathogenic S. marcescens.

Subject headings: Animals; Bombyx; Serratia Infections; Serratia marcescens, Virulence; Virulence Factors; Prodigiosin; Silkworm, Virulence

Publication year: 2016

Journal or book title: Journal of Invertebrate Pathology

Volume: 136

Pages: 92-94

Find the full text: https://www.sciencedirect.com/science/article/abs/pii/S0022201116300271

Find more like this one (cited by): https://scholar.google.com/scholar?cites=9351671967948214376&as_sdt=1000005&sciodt=0,16&hl=en

Serial number: 3678

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