Author: Yao, Run-Wen; Wang, Yang; Chen, Ling-Ling
Description: A diverse catalog of long noncoding RNAs (lncRNAs), which lack protein-coding potential, are transcribed from the mammalian genome. They are emerging as important regulators in gene expression networks by controlling nuclear architecture and transcription in the nucleus and by modulating mRNA stability, translation and post-translational modifications in the cytoplasm. In this Review, we highlight recent progress in cellular functions of lncRNAs at the molecular level in mammalian cells.
Subject headings: Animals; Cell Physiological Phenomena; Gene Regulatory Networks; Genome, Humans; Protein Biosynthesis; Protein Processing, Post-Translational; RNA Stability; RNA, Long Noncoding
Publication year: 2019
Journal or book title: Nature Cell Biology
Volume: 21
Issue: 5
Pages: 542-551
Find the full text: https://www.nature.com/articles/s41556-019-0311-8
Find more like this one (cited by): https://scholar.google.com/scholar?cites=16824812086165975073&as_sdt=1000005&sciodt=0,16&hl=en
Serial number: 3760