Molecular Mechanisms of Bismuth-containing Drugs Against Helicobacter pylori: a Further Update

Author: Liu, Jiahui; Li, Xinhang; Zhu, Yulin; Ge, Ruiguang

Description: Helicobacter pylori (H. pylori) infections cause various gastric diseases in humans, such as gastritis, peptic ulcerations, and even gastric cancer. Bismuth-based triple or quadruple therapies have been commonly recommended for the treatment of H. pylori infections. Up to now, the molecular mechanisms by which bismuth inhibits the growth of H. pylori are far from fully clear.

Subject headings: Helicobacter pylori; Bismuth-containing drug; Enzyme inhibition; Nickel homeostasis; Energy production

Publication year: 2023

Journal or book title: Current Pharmacology Reports

Volume: 9

Issue: 1

Pages: 59-65

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Serial number: 3935