Organocopper Conjugate Addition-Enolate Trapping Reactions

Author: Taylor, Richard J. K.

Description: Conjugate additions reactions between organocopper reagents and ?,?-unsaturated carbonyl compounds are now well established synthetic procedures. This article reviews reactions in which the intermediate enolates are trapped with electrophilic reagents to give ?-substituted enol derivatives or ?,?-disubstituted ketones. The synthetic potential of these products is highlighted. 1. Introduction: Scope and Limitations 2. Silylation and Related O-Enolate Trapping Reactions 3. Enolate Acylation 4. Enolate Alkylation 5. Reactions of Enolates with Michael Acceptors 6. Reactions of Enolates with Aldehydes and Ketones 7. Reactions of Enolates with Miscellaneous Non-Carbon Electrophiles 8. Recent Results 9. Conclusions

Subject headings: Conjugate additions reactions; Organocopper; Synthetic procedures

Publication year: 1985

Journal or book title: Synthesis

Issue: 4

Pages: 364-392

Find the full text: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-1985-31212

Find more like this one (cited by): https://scholar.google.com/scholar?cites=10461082356387817145&as_sdt=1000005&sciodt=0,16&hl=en

Serial number: 3960

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