Author: engeladmin

Author: Barros, V.R.; Boninsegna, J.A.; Camilloni, I.A.; Chidiak, M.; Magrín, G.O.; Rusticucci, M. Description: In most of Argentina, the warming since 1901 was a little lower than the global average, although with strong trends in temperature extremes and in heat waves during the most recent decades. There was a remarkable increase in precipitation over most of subtropical Argentina, especially since 1960. This has favored agriculture yields and the extension of crop lands into semiarid regions, but this increase also came with more frequent heavy rainfalls and consequent flooding of rural…

Description: This graphic represents the projected economic effects of climate change on counties in the United States by 2080-2099. Areas in shades of red are counties that will lose a percentage of their Gross Domestic Product (GDP), while areas in shades of green are counties that may actually increase their GDP. Subject headings: Climate change; Economic damage; Economic effect; United States; Counties Publication year: 2017 Find the full text : https://mlfoe5zv99pn.i.optimole.com/w:auto/h:auto/q:mauto/ig:avif/http://www.strategian.com/fulltext/062917_MT_climate-economics_main.jpg Find more like this one (cited by): https://www.sciencenews.org/article/climate-change-could-exacerbate-economic-inequalities-us#.WVkM4b5C52s.facebook Type: Image Serial number: 1865

Description: This graph shows the increase of carbon dioxide (CO2) levels in the atmosphere from pre-industrial times through March 2016 as measured at Mauna Loa in Hawaii. Subject headings: Climate change; Carbon dioxide; CO2; Atmosphere; Mauna Loa; Hawaii; NOAA Publication year: 2016 Find the full text : https://mlfoe5zv99pn.i.optimole.com/w:auto/h:auto/q:mauto/ig:avif/http://www.strategian.com/fulltext/MaunaLoaCO2.jpg Find more like this one (cited by): https://www.newscientist.com/article/2079995-highest-ever-annual-rise-in-carbon-dioxide-levels-recorded/ Type: Image Serial number: 1846

Description: Past and future sea-level rise. For the past, proxy data are shown in light purple and tide gauge data in blue. For the future, the IPCC projections for very high emissions (red, RCP8.5 scenario) and very low emissions (blue, RCP2.6 scenario) are shown. Source: IPCC AR5 Fig. 13.27. Subject headings: Climate change; Sea level rise Publication year: 2013 Find the full text : https://mlfoe5zv99pn.i.optimole.com/w:auto/h:auto/q:mauto/ig:avif/http://www.strategian.com/fulltext/IPCC_AR5_13.27.png Find more like this one (cited by): http://www.realclimate.org/index.php/archives/2013/10/sea-level-in-the-5th-ipcc-report/comment-page-5/ Type: Image Serial number: 1841

Description: Estimated, observed, and possible future amounts of global sea level rise from 1800 to 2100, relative to the year 2000. Estimates from proxy data (for example, based on sediment records) are shown in red (1800-1890, pink band shows uncertainty), tide gauge data are shown in blue for 1880-2009, and satellite observations are shown in green from 1993 to 2012. The future scenarios range from 0.66 feet to 6.6 feet in 2100. These scenarios are not based on climate model simulations, but rather reflect the range of possible scenarios based…

Description: The graph shows how sea levels will change for four different pathways for human development and greenhouse gas pollution. The green, yellow and orange lines correspond to scenarios where it takes 10, 30, or 70 years before emissions are stabilized. The red line can be considered to represent business as usual where greenhouse gas emissions are increasing over time. Subject headings: Climate change; Sea level rise; Greenhouse gas emissions Publication year: 2013 Find the full text : https://mlfoe5zv99pn.i.optimole.com/w:auto/h:auto/q:mauto/ig:avif/http://www.strategian.com/fulltext/PRfig-EN2.png Find more like this one (cited by): http://www.glaciology.net/Home/PDFs/Announcements/sealevelprojectionstoad2500withthercpscenarios Type: Image Serial number: 1839

Description: Image of the Lyell Glacier, Yellowstone National Park, United States taken in 1883 and 2015. Image courtesy of NASA “Images of Change.” Subject headings: Lyell Glacier; Climate Change; Yellowstone National Park Publication year: 2015 Find the full text : https://mlfoe5zv99pn.i.optimole.com/w:auto/h:auto/q:mauto/ig:avif/http://www.strategian.com/fulltext/Lyell-Glacier-1883-2015.jpg Find more like this one (cited by): https://www.nps.gov/yose/learn/nature/glaciers.htm Type: Image Serial number: 1808

Author: Firsov, A.A.; Strukova, E.N.; Portnoy, Y.A.; Shlykova, D.S.; Zinner, S.H. Description: Emergence of bacterial antibiotic resistance is usually characterized either by population analysis or susceptibility testing. To compare these endpoints in their ability to demonstrate clear relationships with the ratio of 24-h area under the concentration-time curve (AUC24) to the minimum inhibitory concentration (MIC), enrichment of ciprofloxacin-resistant mutants of four clinical isolates of Pseudomonas aeruginosa was studied in an in vitro dynamic model that simulates mono-exponential pharmacokinetics of ciprofloxacin over a wide range of the AUC24/MIC ratios. Each organism…

Author: Tsai, S.Q.; Joung, J.K. Description: CRISPR-Cas9 RNA-guided nucleases are a transformative technology for biology, genetics and medicine owing to the simplicity with which they can be programmed to cleave specific DNA target sites in living cells and organisms. However, to translate these powerful molecular tools into safe, effective clinical applications, it is of crucial importance to carefully define and improve their genome-wide specificities. Here, we outline our state-of-the-art understanding of target DNA recognition and cleavage by CRISPR-Cas9 nucleases, methods to determine and improve their specificities, and key considerations for…

Author: Tang, F.; Barbacioru, C.; Nordman, E.; Li, B.; Xu, N.; Bashkirov, V.I.; Lao, K.; Surani, M.A. Description: We describe here a protocol for digital transcriptome analysis in a single mouse oocyte and blastomere using a deep-sequencing approach. In this method, individual cells are isolated and transferred into lysate buffer by mouth pipette, followed by reverse transcription carried out directly on the whole cell lysate. Free primers are removed by exonuclease I and a poly(A) tail is added to the 3′ end of the first-strand cDNAs by terminal deoxynucleotidyl transferase….