Author: engeladmin

Author: Cairns, K.E.; Yap, M.B.H.; Pilkington, P.D.; Jorm, A.F. Description: BACKGROUND: Adolescence is a peak time for the onset of depression, but little is known about what adolescents can do to reduce their own level of risk. To fill this gap, a review was carried out to identify risk and protective factors for depression during adolescence that are modifiable by the young person. METHODS: Employing the PRISMA method, we conducted a systematic review and meta-analysis of longitudinal studies to identify risk and protective factors during the adolescent period (aged 12-18…

Author: Kawamata, T.; Ren, J.; Chan, T. C.; Charette, M. & Finklestein, S. P. Description: Osteogenic protein-1 (OP-1, BMP-7) is a member of the transforming growth factor-beta (TGF-beta) superfamily that selectively induces dendritic outgrowth from cultured neurons. We injected human recombinant OP-1 (1 or 10 micrograms) or vehicle into the cisterna magna of mature male Sprague-Dawley rats 1 and 4 days after focal cerebral infarction induced by middle cerebral artery (MCA) occlusion. OP-1 treatment was associated with a marked enhancement of recovery of sensorimotor function of the impaired forelimb and…

Author: Kolb, B.; Cote, S.; Ribeiro-da-Silva, A. & Cuello, A. C. Description: This study examined the behavioural and anatomical effects of intraventricular injections of nerve growth factor in rats with unilateral damage that included Zilles’ areas Frl, FL, HL, ParI and the anterior portion of Oc2. Nerve growth factor-treated lesion rats showed attenuation of behavioural symptoms in measures of forelimb function (Whishaw reaching task) and hindlimb function (beam traversing task) as well as a measure of spatial navigation (Morris water task). Analysis of dendritic arborization using a modified Golgi. Cox…

Author: Li, Y.; Chen, J.; Chen, X. G.; Wang, L.; Gautam, S. C.; Xu, Y. X.; Katakowski, M.; Zhang, L. J.; Lu, M.; Janakiraman, N. & Chopp, M. Description: To test the effect of I.V.-injected human bone marrow stromal cells (hMSC) on neurologic functional deficits after stroke in rats. Rats were subjected to transient middle cerebral artery occlusion and IV injected with 3 x 10(6) hMSC 1 day after stroke. Functional outcome was measured before and 1, 7, and 14 days after stroke. Mixed lymphocyte reaction and the development of…

Author: Kovács, Z.; Juhász, G.; Palkovits, M.; Dobolyi, A. & Kékesi, K. A. Description: Nucleosides, such as uridine, inosine, guanosine and adenosine, may participate in the regulation of sleep, cognition, memory and nociception, the suppression of seizures, and have also been suggested to play a role in the pathophysiology of some neurodegenerative and neuropsychiatric diseases. Under pathological conditions, levels of nucleosides change extremely in the brain, indicating their participation in the pathophysiology of disorders like Alzheimer’s disease, Parkinson’s disease and schizophrenia. These findings have resulted in an increasing attention to…

Author: Ritchie, E.G.; Elmhagen, B.; Glen, A.S.; Letnic, M.; Ludwig, G.; McDonald, R.A. Description: Recent advances highlight the potential for predators to restore ecosystems and confer resilience against globally threatening processes, including climate change and biological invasions. However, releasing the ecological benefits of predators entails significant challenges. Here, we discuss the economic, environmental and social considerations affecting predator-driven ecological restoration programs, and suggest approaches for reducing the undesirable impacts of predators. Because the roles of predators are context dependent, we argue for increased emphasis on predator functionality in ecosystems and…

Author: Peters, M.; Schmidt, T.S.; Wiederkehr, D.; Schneider, M. Description: Solar power technologies will have to become a major pillar in the world’s future energy system to combat climate change and resource depletion. However, it is unclear which solar technology is and will prove most viable. Therefore, a comprehensive comparative assessment of solar technologies along the key quantitative and qualitative competitiveness criteria is needed. Based on a literature review and detailed techno-economic modeling for 2010 and 2020 in five locations, we provide such an assessment for the three currently leading…