Search Results for: Memory

Author: Koshino, H.; Kana, R.K.; Keller, T.A.; Cherkassky, V.L.; Minshew, N.J.; Just, M.A. Description: Brain activation and functional connectivity were investigated in high functioning autism using functional magnetic resonance imaging in an n-back working memory task involving photographic face stimuli. The autism group showed reliably lower activation compared with controls in the inferior left prefrontal area (involved in verbal processing and working memory maintenance) and the right posterior temporal area (associated with theory of mind processing). The participants with autism also showed activation in a somewhat different location in the…

Author: Loftus, E.F.; Palmer, J.C. Description: Two experiments are reported in which subjects viewed films of automobile accidents and then answered questions about events occurring in the films. The question, “About how fast were the cars going when they smashed into each other?” elicited higher estimates of speed than questions which used the verbs collided, bumped, contacted, or hit in place of smashed. On a retest one week later, those subjects who received the verb smashed were more likely to say “yes” to the question, “Did you see any broken…

Author: Callicott, J. Description: Functional magnetic resonance imaging (fMRI) is a potential paradigm shift in psychiatric neuroimaging. The technique provides individual, rather than group-averaged, functional neuroimaging data, but subtle methodological confounds represent unique challenges for psychiatric research. As an exemplar of the unique potential and problems of fMRI, we present a study of 10 inpatients with schizophrenia and 10 controls performing a novel “n back” working memory (WM) task. We emphasize two key design steps: (1) the use of an internal activation standard (i.e., a physiological control region) to address…

Author: Baddeley, A.D.; Thomson, N.; Buchanan, M. Description: A number of experiments explored the hypothesis that immediate memory span is not constant, but varies with the length of the words to be recalled. Results showed: (1) Memory span is inversely related to word length across a wide range of materials; (2) When number of syllables and number of phonemes are held constant, words of short temporal duration are better recalled than words of long duration; (3) Span could be predicted on the basis of the number of words which the…

Author: Jonasson, Z. Description: The existence of sex differences in the standard rat and mouse models of learning and memory is a controversial and contested topic in the literature. The present meta-analysis of radial maze and water maze experiments was conducted to assess the reliablility and magnitude of sex effects in the standard rodent models of learning and memory. Data were culled from published and unpublished sources. Findings indicate large reliable male advantages for rats in radial maze and water maze protocols. Significant strain differences were also identified. In each…

Author: D’Hooge, R.; De Deyn, P.P. Description: The Morris water maze (MWM) was described 20 years ago as a device to investigate spatial learning and memory in laboratory rats. In the meanwhile, it has become one of the most frequently used laboratory tools in behavioral neuroscience. Many methodological variations of the MWM task have been and are being used by research groups in many different applications. However, researchers have become increasingly aware that MWM performance is influenced by factors such as apparatus or training procedure as well as by the…

Author: Saltz, E.; Donnenwerth-Nolan, S. Description: Previous studies have shown that motoric enactment of sentences facilitates later sentence retention for both children and adults. While some writers have attributed this effect to the storage of motoric images, other writers have suggested that enactment may stimulate visual imagery or verbal mediation, and that these latter mechanisms may be basic to the facilitated memory. The present study was designed to distinguish among motoric imagery, visual imagery, and verbal mediation by means of a series of selective interference tests. In Experiment 1, 112…

Author: Stancampiano, R.; Cocco, S.; Cugusi, C.; Sarais, L.; Fadda, F. Description: By using in vivo microdialysis we monitored the extracellular levels of acetylcholine and serotonin in the hippocampus of rats performing a spatial memory task. After rats were trained for 10 consecutive days to master a food-reinforced radial-arm maze task, they were implanted with a microdialysis probe in the dorsal hippocampus. On day 12, rats were tested in the maze and acetylcholine and serotonin outputs were monitored before the test, during the waiting phase and while performing the trials….

Author: Gisquet-Verrier, P.; Delatour, B. Description: Contrary to human and primate, working memory in the rodent is usually considered as a simple short term memory buffer and mainly investigated using delayed response paradigms. The aim of the present study was to further investigate the role of the rat prelimbic/infralimbic cortex in different spatial delayed tasks in order to dissociate its involvement in temporary storage from other information processes, such as behavioral flexibility and attention. In experiment 1 rats were trained in a standard elimination win-shift task in a radial-arm maze…

Author: Sampedro-Piquero, P.; Zancada-Menendez, C.; Begega, A.; Rubio, S.; Arias, J.L. Description: We have studied the effect of an environmental enrichment (EE) protocol in adult Wistar rats on the activity in the elevated zero-maze (EZM), performance in the radial-arm water maze (RAWM) and we have also examined the changes in the neuronal metabolic activity of several brain regions related to anxiety response and spatial memory through cytochrome c oxidase histochemistry (COx). Our EE protocol had anxiolytic effect in the EZM; the animals spent more time and made more entries into…