Author: engeladmin

Lee, A., Liew, M.S. (2020) Journal of Material Cycles and Waste Management, 22(1), 1-10 The accumulation of plastic waste is a pressing environmental problem, growing hand-in-hand with the rising production and consumption of consumer products. The robustness and intrinsic strength of plastics, which render them extremely useful in various packaging applications, are a double-edged sword as they are likewise highly resistant to degradation and may persist for several millennia. Conventional waste treatment solutions are increasingly unable to manage the growing volume of such waste, bringing us to the brink of…

Sharma, A., Kumar, P. (2018) Environment International,120, 262-278 Air pollution exposure to in-pram babies poses a serious threat to their early childhood development, necessitating a need for effective mitigation measures. We reviewed the scientific and grey literature on in-pram babies and their personal exposure to traffic generated air pollutants such as particulate matter </=10mum (PM10), </=2.5mum (PM2.5), </=0.10mum (ultrafine particles) in size, black carbon and nitrogen oxides and potential mitigation pathways. In-pram babies can be exposed up to ~60% higher average concentrations depending on the pollutant types compared with adults….

Myers, A.G., Zhong, B., Movassaghi, M., Kung, D.W., Lanman, B.A., Kwon, S. (2000) Tetrahedron Letters, 41(9), 1359-1362 The Dess–Martin periodinane was found to be a superior oxidant for the efficient, epimerization-free synthesis of optically active N-protected [alpha]-amino aldehydes from the corresponding N-protected [alpha]-amino alcohols. Highly racemization-prone products, including N-Fmoc phenylglycinal and N-trifluoroacetyl 9alpha]-amino aldehydes, were prepared in >95% yield with <1% epimerization. Subject Headings: Amino aldehydes; High enantiomeric excess; Epimerizable Find the full text: https://www.sciencedirect.com/science/article/pii/S0040403999022935 Find more like this one (cited by): https://scholar.google.com/scholar?cites=5731774568645252975&as_sdt=1000005&sciodt=0,16&hl=en Type: Journal Article Serial number: 2542

Morkunas, M., Dube, L., Götz, F., Maier, M.E. (2013) Tetrahedron, 69(40), 8559-8563 In a sequential three-component coupling syncarpic acid, 3-methylbutanal and an acylated phloroglucinol were combined to the hydroxy ketone 3. Acid catalysis converted 3 directly to the natural product rhodomyrtosone B. The other isomer, the antibiotic rhodomyrtone was obtained from 3 in a sequence of acid-catalyzed cyclization, retro Friedel-Crafts reaction, and reacylation. In preliminary assays both compounds showed potent antibiotic activity. Subject headings: Acylphloroglucinols; Natural products; Antibiotics; Knoevenagel condensation; Retro Friedel-Crafts acylation Find the full text: http://www.sciencedirect.com/science/article/pii/S0040402013012258 Find more…

Lee, S., Kim, H.-S., Min, H.; Pyo, A. (2016) Tetrahedron Letters, 57(2), 239-242 Benzoylacetonitrile were prepared through sequential carbonylation and decarboxylation. The palladium-catalyzed carbonylation of aryl iodides and methyl cyanoacetate using Mo(CO)6 as a carbon monoxide source afforded beta-keto cyanoesters, and then the subsequent reaction with Li/H2O produced the desired benzoylacetonitriles. Subject headings: Benzoylacetonitrile; Palladium; Decarboxylation; Carbonylation; Aryl iodide Find the full text: http://www.sciencedirect.com/science/article/pii/S0040403915304652 Find more like this one (cited by): https://scholar.google.com/scholar?cites=13085745098298914623&as_sdt=1000005&sciodt=0,16&hl=en Type: Journal Article Serial number: 1495

Outram, S., Graves, J.L., Powell, J., Wolpert, C., Haynie, K.L., Foster, M.W., Blanchard, J.W., Hoffmeyer, A., Agans, R.P., Royal, C.D.M. (2018) Race and Social Problems, 10(2), 79-90 Concerns have been raised that the increase in popular interest in genetics may herald a new era within which racial inequities are seen as “natural” or immutable. In the following study, we provide data from a nationally representative survey on how the US population perceives general ability, athleticism, and intellect being determined by race and/or genetics and whether they believe racial health inequities…

Bisht, K., Sharma, K., Tremblay, M.E. (2018) Neurobiology of Stress, 9, 9-21 Microglia are the predominant immune cells of the central nervous system (CNS) that exert key physiological roles required for maintaining CNS homeostasis, notably in response to chronic stress, as well as mediating synaptic plasticity, learning and memory. The repeated exposure to stress confers a higher risk of developing neurodegenerative diseases including sporadic Alzheimer’s disease (AD). While microglia have been causally linked to amyloid beta (Abeta) accumulation, tau pathology, neurodegeneration, and synaptic loss in AD, they were also attributed…

Ha, S., Yeung, E., Bell, E., Insaf, T., Ghassabian, A., Bell, G., Muscatiello, N., Mendola, P. (2019) Environmental Research, 174, 170-175 BACKGROUND: Residential proximity to major roadways, and prenatal exposures to particulate matter <2.5mum (PM2.5) and ozone (O3) are linked to poor fetal outcomes but their relationship with childhood development is unclear. OBJECTIVES: We investigated whether proximity to major roadways, or prenatal and early-life exposures to PM2.5 and O3 increase the risk of early developmental delays. STUDY DESIGN: Prospective cohort. SETTINGS: New York State excluding New York City. PARTICIPANTS: 4089…

Weisleder, A., Mazzuchelli, D.S.R., Lopez, A.S., Neto, W.D., Cates, C.B., Goncalves, H.A., Fonseca, R.P., Oliveira, J., Mendelsohn, A.L. (2018) Pediatrics, 141(1), e20170723 OBJECTIVES: Many children in low- and middle-income countries fail to reach their developmental potential. We sought to determine if a parenting program focused on the promotion of reading aloud enhanced parent-child interactions and child development among low-income families in northern Brazil. METHODS: This was a cluster-randomized study of educational child care centers randomly assigned to receive an additional parenting program (intervention) or standard child care without a parenting…

Henkenius, K., Greene, B.H., Barckhausen, C., Hartmann, R., Marken, M., Kaiser, T., Rehberger, M., Metzelder, S.K., Parak, W.J., Neubauer, A., Brendel, C., Mack, E. (2017) Leukemia Research, 62, 56-63 Primary resistance to induction therapy is an unsolved clinical problem in acute myeloid leukemia (AML). Here we investigated drug resistance in AML at the level of cellular metabolism in order to identify early predictors of therapeutic response. Using extracellular flux analysis, we compared metabolic drug responses in AML cell lines sensitive or resistant to cytarabine or sorafenib after 24h of drug…