Tag: Glyphosate

Cleaning the scientific house: Rebuilding trust in science requires confronting the harms of ghostwriting

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Author: Oreskes, N Description: “Consider the problem of ghostwriting in science. Recently, a colleague and I published a paper analyzing the impacts of a peer-reviewed paper, published in 2000, that purported to be an independent, objective, and comprehensive review of the safety of the pesticide, glyphosate. The paper found no convincing evidence for toxicity, genotoxicity, carcinogenicity, or endocrine disruption. However, documents made public through legal proceedings in 2017 showed that the paper was not, in fact, independent, but had been conceptualized and largely written by Monsanto employees. We wanted to…

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The herbicide glyphosate is a potent inhibitor of 5-enolpyruvylshikimic acid-3-phosphate synthase

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Author: Steinrucken, H. C.; Amrhein, N. Description: The broadspectrum herbicide glyphosate (N-[phosphonomethyl]-glycine), which causes the accumulation of shikimic acid in plant tissues, inhibits the enzymatic conversion of shikimic acid to anthranilic acid in a cell-free extract of Aerobacter, aerogenes 50% at 5 to 7 uM concentrations. Of the four enzymes involved in the transformation, only 5-enolpyruvylshikimic acid-3-phosphate synthase is inhibited by the herbicide. Subject headings: Enzymes; Glyphosate; Metabolism; Physiology; Weeds; Plants; Eukaryotes Publication year: 1980 Journal or book title: Biochemical and Biophysical Research Communications Volume: 94 Issue: 4 Pages: 1207-1212…

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