Tag: OCD

Experimentally induced and real-world anxiety have no demonstrable effect on goal-directed behaviour

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Author: Gillan, C. M.; Vaghi, M. M.; Hezemans, F. H.; van Ghesel Grothe, S.; Dafflon, J.; Bruhl, A. B.; Savulich, G.; Robbins, T. W. Description: BACKGROUND: Goal-directed control guides optimal decision-making and it is an important cognitive faculty that protects against developing habits. Previous studies have found some evidence of goal-directed deficits when healthy individuals are stressed, and in psychiatric conditions characterised by compulsive behaviours and anxiety. Here, we tested if goal-directed control is affected by state anxiety, which might explain the former results. METHODS: We carried out a causal…

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All cause and cause specific mortality in obsessive-compulsive disorder: nationwide matched cohort and sibling cohort study

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Author: Fernandez de la Cruz, Lorena; Isomura, Kayoko; Lichtenstein, Paul; Larsson, Henrik; Kuja-Halkola, Ralf; Chang, Zheng; D’Onofrio, Brian M.; Brikell, Isabell; Ruck, Christian; Sidorchuk, Anna; Mataix-Cols, David Description: OBJECTIVE: To estimate the risk of all cause and cause specific mortality in people with obsessive-compulsive disorder (OCD) compared with matched unaffected people from the general population and with their unaffected siblings. DESIGN: Population based matched cohort and sibling cohort study. SETTING: Register linkage in Sweden. PARTICIPANTS: Population based cohort including 61 378 people with OCD and 613 780 unaffected people matched (1:10) on…

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