Tag: Heterocycles

Synthesis of Phosphorus and Sulfur Heterocycles via Ring-Closing Olefin Metathesis

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Author: McReynolds, Matthew D.; Dougherty, Joseph M.; Hanson, Paul R. Description: Organophosphorus compounds continue to receive widespread attention due to their ubiquity in biological systems and their potential to serve as novel pharmaceutical, agricultural, and chemical agents. Among these, a number of phosphorus heterocycles (P-heterocycles) displaying potent biological activity have emerged. Subject headings: Catalysts; Group 15 compounds; Metathesis; Organophosphorous compounds; Sulfones Publication year: 2004 Journal or book title: Chemical Reviews Volume: 104 Issue: 5 Pages: 2239-2258 Find the full text: https://pubs.acs.org/doi/full/10.1021/cr020109k Find more like this one (cited by): https://scholar.google.com/scholar?cites=2086459361865661873&as_sdt=1000005&sciodt=0,16&hl=en Serial…

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Role of sulphur-heterocycles in medicinal chemistry: An update

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Author: Pathania, Shelly; Narang, Raj Kumar; Rawal, Ravindra K. Description: From many decades, S-heterocycles have maintained their status as an important part and core of FDA approved drugs and medicinally active compounds. With exhaustive exploration of nitrogen heterocycles in medicinal chemistry, researchers have shifted their interest towards other heterocycles, especially, S-heterocycles. Thus several attempts have been made to synthesize a variety of new sulphur containing compounds with high medicinal value and low toxicity profile, in comparison to previous N-heterocycles. Till today, S-heterocycle containing compounds have been largely reported as anticancer,…

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